Coronary arterial calcification is associated with albuminuria in type 2 diabetic patient
Autor: | T. Sato, M. Miyamoto, M. Fukumoto, M. Hosoi, K. Yamagami, T. Ishii, Shiro Tanaka, T. Yamamoto, S. Fujii, K. Yoshioka, T. Yamakita |
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Rok vydání: | 2005 |
Předmět: |
Male
medicine.medical_specialty Time Factors Endocrinology Diabetes and Metabolism Aortic Diseases Blood Pressure Coronary Artery Disease Nephropathy Body Mass Index Diabetic nephropathy Endocrinology Risk Factors Diabetes mellitus Internal medicine Internal Medicine medicine Albuminuria Humans Diabetic Nephropathies Coronary atherosclerosis business.industry Smoking Age Factors Calcinosis Cholesterol LDL Middle Aged medicine.disease Arterial calcification Blood pressure Diabetes Mellitus Type 2 Creatinine Cardiology Microalbuminuria Female medicine.symptom business Tomography X-Ray Computed |
Zdroj: | Diabetes, obesitymetabolism. 7(4) |
ISSN: | 1462-8902 |
Popis: | Aim: Although microalbuminuria has been suggested as an independent risk factor for ischemic heart disease, the relationship between diabetic nephropathy and macroangiopathy remains unclear. Previously, we reported that coronary artery calcification detected by electron beam computed tomography (EBCT) could indicate the degree of coronary atherosclerosis in type 2 diabetic patients. In this study, we examine the association between coronary arterial calcification and microalbuminuria and aortic calcification and microalbuminuria. Methods: Two hundred and fifty-six patients, including 177 type 2 diabetic patients (106 patients with normoalbuminuria, 71 with microalbuminuria) and 79 non-diabetic patients were evaluated by assessing the urinary albumin excretion rate and using EBCT to determine a coronary calcification score (CCS) and an aortic calcification score (ACS). Results: No differences were observed regarding age, smoking index or BMI. Diabetic patients exhibited a greater CCS than non-diabetic subjects (non-diabetes 33 ± 75 vs. diabetes 203 ± 467, p |
Databáze: | OpenAIRE |
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