Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activity decay following cycloheximide administration
| Autor: | M.F. Zuretti, Enrico Gravela, O. Brossa |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
Testosterone propionate medicine.medical_specialty medicine.medical_treatment In Vitro Techniques Thioacetamide Biology Cycloheximide Kidney Ornithine Decarboxylase Ornithine decarboxylase Mice chemistry.chemical_compound Liver Neoplasms Experimental Internal medicine medicine Animals Hepatectomy Mammary Neoplasms Experimental Rats Inbred Strains Neoplasms Experimental Cell Biology Liver regeneration Liver Regeneration Rats medicine.anatomical_structure Endocrinology Liver chemistry Female Polyamine |
| Zdroj: | Cell Biology International Reports. 11:573-582 |
| ISSN: | 0309-1651 |
| DOI: | 10.1016/0309-1651(87)90137-8 |
| Popis: | We have studied the activity, thiol-dependency and Km of ornithine decarboxylase (ODC) from the following sources: liver of rats subjected to partial hepatectomy or administered thioacetamide, the rat 3924A Morris hepatoma, the rat AH130 Yoshida ascites hepatoma, a mouse transplantable mammary carcinoma and kidney of rats administered testosterone propionate. In order to detect possible changes occurring during in vivo ageing of this enzyme we inhibited protein synthesis with cycloheximide. A gradual decrease of Km during ageing was observed in ODC from liver. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|