Correlation of serum and salivary cortisol levels in prepubertal school-aged children
| Autor: | Alison Tait, Sheldon H. Preskorn, Elizabeth B. Weller, Ronald A. Weller, John F. Bober, Mary A. Fristad |
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| Rok vydání: | 1988 |
| Předmět: |
Male
medicine.medical_specialty Depressive Disorder School age child Hydrocortisone Specific time Serum samples Dexamethasone Correlation Psychiatry and Mental health Endocrinology Dexamethasone suppression test Internal medicine Developmental and Educational Psychology medicine Humans Female Psychology Child Saliva Salivary cortisol Blood sampling medicine.drug |
| Zdroj: | Journal of the American Academy of Child and Adolescent Psychiatry. 27(6) |
| ISSN: | 0890-8567 |
| Popis: | The dexamethasone suppression test (DST) is useful in assessing major depression in children, but it requires blood sampling, which is unpleasant. Two studies have demonstrated strong correlations between serum and salivary cortisol levels in combined samples of children and adolescents administered DSTs. The present study replicated these findings in 15 prepubertal children. Overall, serum and salivary samples were significantly correlated, as were those from specific time periods ( r = 0.86 to 0.97). A salivary cortisol level of 0.14 μg/dl separated DST nonsuppressors from suppressors. Salivary cortisol samples could be used in place of serum samples when performing the DST. |
| Databáze: | OpenAIRE |
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