Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study
| Autor: | Anatoly Lebedev, Olga Kuznetsova, Elena Andreeva, M A Pokhaznikova, Jean-Marie Degryse, Irina E. Moiseeva |
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| Přispěvatelé: | UCL - SSS/IRSS - Institut de recherche santé et société, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Spirometry medicine.medical_specialty medicine.drug_class Vital Capacity Population Physical examination Article Russia law.invention Pulmonary Disease Chronic Obstructive 03 medical and health sciences FEV1/FVC ratio 0302 clinical medicine law Forced Expiratory Volume Internal medicine Bronchodilator medicine Humans 030212 general & internal medicine education Asthma lcsh:RC705-779 education.field_of_study COPD medicine.diagnostic_test business.industry IRSS Public Health Environmental and Occupational Health lcsh:Diseases of the respiratory system Middle Aged respiratory system medicine.disease Bronchodilator Agents respiratory tract diseases Cross-Sectional Studies 030228 respiratory system Female business Spirometer Follow-Up Studies |
| Zdroj: | npj Primary Care Respiratory Medicine, Vol 27, Iss 1, Pp 1-9 (2017) N P J Primary Care Respiratory Medicine, Vol. 27, no. 1, p. 62 [1-9] (2017) NPJ Primary Care Respiratory Medicine |
| ISSN: | 2055-1010 |
| DOI: | 10.1038/s41533-017-0062-6 |
| Popis: | A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD diagnosis has been based on spirometry and a few clinical characteristics. The aim of our study was to identify outcomes in patients newly diagnosed with airflow obstruction (AO) based on a diagnostic work-up conducted as part of a population-based cross-sectional study in North-Western Russia. Spirometry was performed before (pre-BD) and after BD administration, and AO was defined using the FEV1/FVC COPD: Single lung function test not enough for diagnosis A single lung function test is insufficient to accurately diagnose chronic obstructive pulmonary disease (COPD). A team led by Jean-Marie Degryse from the Université Catholique de Louvain, Belgium, studied patients in Northwestern Russia who showed signs of airflow obstruction, as measured by a spirometer, a medical device that records the amount of air inhaled and exhaled and the speed of breath. Among those who initially showed signs of limited lung function, even after treatment with a bronchodilator, a large proportion did not exhibit airflow obstruction on a second spirometry test months later. Moreover, not everyone who had confirmed airflow obstruction were diagnosed with COPD when examined by a pulmonologist. Some had asthma or asthma-COPD overlap syndrome. The findings point to the need for clinical assessments and follow-up spirometry tests to accurately diagnose and manage COPD. |
| Databáze: | OpenAIRE |
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