A New Approach to the Synthesis of 2,6-Dichloro-3-Fluorobenzonitrile: A Useful Pharmaceutical Intermediate

Autor: Zhiwei Chen, Weike Su, Lidong Zheng
Rok vydání: 2011
Předmět:
Zdroj: Journal of Chemical Research. 35:474-476
ISSN: 2047-6507
1747-5198
DOI: 10.3184/174751911x13129873455321
Popis: A highly efficient manufacturing-scale process for the preparation of 2,6-dichloro-3-fluorobenzonitrile, utilising industrial by-product 2,6-dichloro-3-fluoroacetophenone as starting material, has been developed. The overall yield was 77%.
Databáze: OpenAIRE