A Randomised Trial Examining Cardiovascular Morbidity and All-Cause Mortality 24 years Following General Health Checks: the Ebeltoft Health Promotion Project (EHPP)
| Autor: | Torsten Lauritzen, Else-Marie Dalsgaard, Martin Bernstorff, Niels Henrik Bruun, Pia Deichgræber, Morten Fenger-Grøn |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty hypertension Denmark Population General Practice Psychological intervention Health Promotion preventive medicine organisation of health services law.invention Danish 03 medical and health sciences primary care 0302 clinical medicine Randomized controlled trial law Epidemiology Outcome Assessment Health Care Preventive Health Services medicine Humans 030212 general & internal medicine education Preventive healthcare Original Research education.field_of_study business.industry Public health public health General Medicine Middle Aged language.human_language Survival Rate Health promotion Cardiovascular Diseases Family medicine language epidemiology Female business General practice / Family practice 030217 neurology & neurosurgery |
| Zdroj: | BMJ Open Bernstorff, M, Deichgræber, P, Bruun, N H, Dalsgaard, E-M, Fenger-Grøn, M & Lauritzen, T 2019, ' A Randomised Trial Examining Cardiovascular Morbidity and All-Cause Mortality 24 years Following General Health Checks : the Ebeltoft Health Promotion Project (EHPP) ', BMJ Open, vol. 9, no. 10, e030400 . https://doi.org/10.1136/bmjopen-2019-030400 |
| ISSN: | 2044-6055 |
| Popis: | IntroductionGlobal prevalence of risk factors for cardiovascular disease (CVD) and all-cause mortality is increasing. Treatments are available but can only be implemented if individuals at risk are identified. General health checks have been suggested to facilitate this process.ObjectivesTo examine the long-term effect of population-based general health checks on CVD and all-cause mortality.Design and settingThe Ebeltoft Health Promotion Project (EHPP) is a parallel randomised controlled trial in a Danish primary care setting.ParticipantsThe EHPP enrolled individuals registered in the Civil Registration System as (1) inhabitants of Ebeltoft municipality, (2) registered with a general practitioner (GP) participating in the study and (3) aged 30–49 on 1 January 1991. A total of 3464 individuals were randomised as invitees (n=2000) or non-invitees (n=1464). Of the invitees, 493 declined. As an external control group, we included 1 511 498 Danes living outside the municipality of Ebeltoft.InterventionsInvitees were offered a general health check and, if test-results were abnormal, recommended a 15–45 min consultation with their GP. Non-invitees in Ebeltoft received a questionnaire at baseline and were offered a general health check at year 5. The external control group, that is, the remaining Danish population, received routine care only.Outcome measuresHRs for CVD and all-cause mortality.ResultsEvery individual randomised was analysed. When comparing invitees to non-invitees within the municipality of Ebeltoft, we found no significant effect of general health checks on CVD (HR=1.11 (0.88; 1.41)) or all-cause mortality (HR=0.93 (0.75; 1.16)). When comparing invitees to the remaining Danish population, we found similar results for CVD (adjusted HR=0.99 (0.86; 1.13)) and all-cause mortality (adjusted HR=0.96 (0.85; 1.09)).ConclusionWe found no effect of general health checks offered to the general population on CVD or all-cause mortality.Trial registration numberNCT001457822015-57-0002; 62908, 187. |
| Databáze: | OpenAIRE |
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