A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile

Autor: Marcela Zuñiga, Anne J Lagomarcino, Sergio Muñoz, Alfredo Peña Alonso, María Andrea Rodriguez, Miguel L O'Ryan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical Epidemiology
ISSN: 1878-5921
0895-4356
Popis: Objective Healthcare workers (HCWs) are at increased risk for SARS-CoV-2 infection, however not all face the same risk. We aimed to determine IgG/IgM prevalence and risk factors associated with seropositivity in Chilean HCWs. Study Design and Setting This was a nationwide, cross-sectional study including a questionnaire and COVID-19 lateral flow IgG/IgM antibody testing. All HCWs in the Chilean public health care system were invited to participate following the country's first wave. Results IgG/IgM positivity in 85,529 HCWs was 7.2%, ranging from 1.6% to 12.4% between regions. Additionally, 9.7% HCWs reported a positive PCR of which 47% were seropositive. Overall, 10,863 (12.7%) HCWs were PCR and/or IgG/IgM positive.Factors independently associated with increased odds ratios (ORs) for seropositivity were: working in a hospital, night shifts, contact with Covid-19, using public transport, male gender, age>45, BMI ≥30, and reporting ≥2 symptoms. Stress/mental health disorder and smoking were associated with decreased ORs. These factors remained significant when including PCR positive cases in the model. Conclusions HCWs in the hospital were at highest risk for COVID-19, and several independent risk factors for seropositivity and/or PCR positivity were identified.
Databáze: OpenAIRE
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