The Incidence and Prognosis of Renal Dysfunction following Cardioversion of Atrial Fibrillation
Autor: | Chaim Lotan, Mohamad Afifi, Shimon Rosenheck, Arthur Pollak, David Leibowitz, S. Loncar, Matan J. Cohen, Yosef S. Haviv, Guy Haber, David Gozal, Yaron Hellman, Dan Gilon |
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Rok vydání: | 2013 |
Předmět: |
Male
medicine.medical_specialty business.industry Incidence (epidemiology) medicine.medical_treatment Electric Countershock Atrial fibrillation macromolecular substances Acute Kidney Injury Prognosis medicine.disease Cardioversion Survival Analysis Case-Control Studies Internal medicine Atrial Fibrillation Multivariate Analysis medicine Cardiology Humans Female Pharmacology (medical) Cardiology and Cardiovascular Medicine business Aged |
Zdroj: | Cardiology. 124:184-189 |
ISSN: | 1421-9751 0008-6312 |
DOI: | 10.1159/000346618 |
Popis: | Objective: Limited data are available regarding the incidence and clinical impact of renal dysfunction following cardioversion of atrial fibrillation. The objective of this study was to assess the incidence and implications of renal dysfunction following cardioversion of atrial fibrillation. Methods: We conducted a nested case-control study to determine the incidence, timing, risk factors and outcome of atrial fibrillation cardioversion associated with renal dysfunction (AFCARD) in a tertiary medical center. Consecutive patients undergoing direct current cardioversion (DCCV) for atrial fibrillation in our institution during 2008-2009 with measurements of creatinine before and following cardioversion were included. AFCARD was defined as a rise in serum creatinine greater than 25% from baseline within a week following DCCV. Results: One hundred and twelve patients were included in the study, of whom 19 (17%) developed AFCARD. One patient required hemodialysis. Patients with AFCARD had a higher incidence of advanced heart failure, diabetes mellitus and were more frequently treated with digoxin and enoxaparin. Patients with AFCARD had a significantly decreased survival rate at 1 year (63 vs. 92%; p < 0.001). Conclusions: AFCARD is relatively common and is associated with increased mortality. These findings suggest a role for close surveillance of renal function following DCCV. |
Databáze: | OpenAIRE |
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