Anti-vascular endothelial growth factors for choroidal neovascularization secondary to choroidal osteoma: Long-term results
| Autor: | N Sarwate Renuka, Hari Narayan Prasad, T Lekha |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
intravitreal bevacizumab
medicine.medical_specialty Choroidal neovascularization genetic structures Case Report lcsh:Ophthalmology Ophthalmology medicine Intravitreal bevacizumab Osteoma intravitreal ranibizumab Endothelial Growth Factors medicine.diagnostic_test business.industry Choroidal osteoma Long term results Fluorescein angiography medicine.disease eye diseases lcsh:RE1-994 choroidal osteoma sense organs Ranibizumab medicine.symptom business medicine.drug |
| Zdroj: | Oman Journal of Ophthalmology, Vol 8, Iss 3, Pp 185-187 (2015) Oman Journal of Ophthalmology |
| ISSN: | 0974-620X |
| DOI: | 10.4103/0974-620x.169908 |
| Popis: | Choroidal osteoma is an uncommon benign osseous intraocular tumor typically seen unilaterally in young women. Visual loss can occur due to choroidal neovascularization (CNV) complicating osteoma. We report a rare case of bilateral choroidal osteoma with secondary CNV in a young male and the long-term results following anti-vascular endothelial growth factor (VEGF) therapy. A 30-year-old male with history of defective vision in both eyes since several years and recent worsening in the right eye (RE) since 2 months was found to have bilateral macular osteoma with CNV in the RE based on clinical evaluation, fluorescein angiography, optical coherence tomography, and ultrasonography. Intravitreal injection of ranibizumab at monthly intervals for three doses resulted in resolution of CNV and remained stable for 5 years. Recurrent CNV detected 6 years later responded to an injection of intravitreal bevacizumab and has remained stable till date. Anti-VEGF therapy stabilized the secondary CNV in our patient for 7 years with satisfactory structural and functional outcome, demonstrating the long-term efficacy of this modality of treatment. |
| Databáze: | OpenAIRE |
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