Simultaneous Improvement of Minimal-Change Nephrotic Syndrome and Anemia with Steroid Therapy
| Autor: | Machiko Yabana, Minoru Kihara, Katsumi Matsumoto, Satoshi Umemura, Nobuyoshi Takagi, Masao Ishii, Seiko Kamijo, Kouichi Tamura, Yoshiyuki Toya |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Anemia Prednisolone Urinary system Anti-Inflammatory Agents Kidney Function Tests hemic and lymphatic diseases Internal medicine Humans Medicine Erythropoietin Blood urea nitrogen business.industry Nephrosis Lipoid Glomerulonephritis Middle Aged medicine.disease Proteinuria Endocrinology Hemoglobin business Nephrotic syndrome medicine.drug Kidney disease |
| Zdroj: | Nephron. 81:84-88 |
| ISSN: | 2235-3186 1660-8151 |
| Popis: | A 56-year-old man presented with transient anemia in minimal-change nephrotic syndrome. Following nephrotic syndrome, anemia suddenly appeared without renal dysfunction. The anemia might be attributable to hemodilution because of significant correlations between the values of hemoglobin concentration and serum total protein or blood urea nitrogen during the clinical course. A low serum level and a low urinary excretion of erythropoietin were found, and when nephrotic syndrome ameliorated with steroid therapy, urinary erythropoietin excretion and anemia disappeared. This case indicated disappearance of the exponential increase of endogenous erythropoietin in acute anemia in nephrotic syndrome probably due to urinary losses and altered biosynthesis of erythropoietin. We report a case of the simultaneous improvement of both nephrotic syndrome and anemia with steroid therapy. |
| Databáze: | OpenAIRE |
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