Predicting remission of diabetes post metabolic surgery: a comparison of ABCD, diarem, and DRS scores
| Autor: | Kajari Majumdar, Ghanshyam Goyal, Om Tantia, Anmol Ahuja, Shashi Khanna, Tamonas Chaudhuri, Shivakumar Seetharamaiah |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate analysis Time Factors endocrine system diseases Adolescent Endocrinology Diabetes and Metabolism Gastric Bypass Bariatric Surgery 030209 endocrinology & metabolism 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine Diabetes mellitus Retrospective analysis Medicine Humans Obesity Protein Precursors Aged Retrospective Studies Glycated Hemoglobin Nutrition and Dietetics ABCD² score Receiver operating characteristic C-Peptide business.industry Metabolic surgery Significant difference Remission Induction nutritional and metabolic diseases Middle Aged medicine.disease Prognosis Obesity Morbid Treatment Outcome Diabetes Mellitus Type 2 ROC Curve 030211 gastroenterology & hepatology Surgery Female business |
| Zdroj: | Obesity surgery. 28(7) |
| ISSN: | 1708-0428 |
| Popis: | Obesity is one of the major causes for development of T2DM. Metabolic surgery has been proved to be a successful and cost-effective treatment modality for managing the patients with obesity and T2DM. Many scoring systems and models have been described in literature to predict the outcome of T2DM after metabolic surgery. The aim of this study is to compare the efficacy of Diarem, DRS, and ABCD score in predicting the T2DM remission. A total number of 102 diabetic patients, who underwent LMGB/LOAGB, were selected for this study. A retrospective analysis of the three scoring systems when applied to these patients and their predictive abilities were analyzed. At 1 year after surgery, 72 (70.59%) patients achieved remission of T2DM. Though the pairwise comparisons between AUC on ROC analysis of ABCD, Diarem, and DRS scores does not show statistically significant difference between them, Diarem score has the maximum relative area under ROC curves. By multivariate analysis, it was found that factors significantly associated with T2DM remission were duration of T2DM, C-peptide, and Pre-Op HbA1c. Among the three scoring systems, though DiaRem score has the best sensitivity and specificity and maximum AUC, no statistically significant difference was found in their diabetes remission predicting abilities. A shorter duration of T2DM, a lower HbA1C, and higher levels of C-peptide were significantly associated with a higher chance of T2DM remission. |
| Databáze: | OpenAIRE |
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