Computed tomographic colonography with a reduced dose of laxative using a novel barium sulfate contrast agent in Japan
| Autor: | Tsuyoshi Morimoto, Katsuhiko Mitsuzaki, Gen Iinuma, Hideto Tomimatsu, Mototaka Miyake |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_treatment Laxative Contrast Media Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Japan Positive predicative value Surveys and Questionnaires Medicine Humans Radiology Nuclear Medicine and imaging Computed Tomographic Colonography Aged business.industry Fecal occult blood Reproducibility of Results Middle Aged Reduced dose digestive system diseases Radiographic Image Enhancement Barium sulfate chemistry Optical colonoscopy Laxatives 030220 oncology & carcinogenesis Bowel preparation Female Barium Sulfate business Nuclear medicine Colonography Computed Tomographic |
| Zdroj: | Japanese journal of radiology. 37(3) |
| ISSN: | 1867-108X |
| Popis: | To test the tagging efficacy, patient acceptability, and accuracy of computed tomographic colonography (CTC) with a reduced dose of laxative using a novel barium sulfate (BaSO4) contrast agent. CTC followed by optical colonoscopy (OC) was performed on 73 patients with positive results in fecal occult blood tests. They were administrated a BaSO4 suspension and a magnesium citrate solution for bowel preparation. Patients completed a questionnaire about the acceptability of bowel preparation. Tagging efficacy was estimated using a novel categorization system, which classified all segments into 8 categories. The accuracy of detecting protruded lesions ≥ 6 mm was calculated from the comparison of CTC and OC results, using the latter as a reference standard. Tagging efficacy was good in 77.3% of colonic segments where residue was observed. The acceptability of bowel preparation for CTC was significantly higher than that for OC. The sensitivity, specificity, and positive and negative predictive values were 0.778, 0.945, 0.824, and 0.929, respectively. All lesions ≥ 7 mm were successfully detected by CTC. CTC with a reduced dose of laxative using a novel BaSO4 contrast agent has a favorable tagging efficacy, patient acceptability, and accuracy. |
| Databáze: | OpenAIRE |
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