MEASURING INTRAOCULAR PRESSURE IN WHITE'S TREE FROGS (LITORIA CAERULEA) BY REBOUND TONOMETRY: COMPARING DEVICE, TIME OF DAY, AND MANUAL VERSUS CHEMICAL RESTRAINT METHODS
| Autor: | Ashley R. Krisp, Jennifer C. Hausmann, Christoph Mans, Kurt K. Sladky, Paul E. Miller |
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| Rok vydání: | 2017 |
| Předmět: |
Restraint
Physical medicine.medical_specialty Intraocular pressure genetic structures Ranidae 040301 veterinary sciences Glaucoma 0403 veterinary science 03 medical and health sciences Tonometry Ocular 0302 clinical medicine Time of day Chemical restraint Ophthalmology medicine Animals Aminobenzoates Circadian rhythm Intraocular Pressure Anesthetics General Veterinary biology Dose-Response Relationship Drug business.industry 04 agricultural and veterinary sciences General Medicine REBOUND TONOMETRY Litoria caerulea medicine.disease biology.organism_classification eye diseases Circadian Rhythm 030221 ophthalmology & optometry Animal Science and Zoology sense organs business |
| Zdroj: | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 48(2) |
| ISSN: | 1042-7260 |
| Popis: | Ocular diseases reported in frogs include uveitis and glaucoma, which are associated with changes in intraocular pressure (IOP). The objectives of this study were to characterize the normal IOP for White's tree frogs ( Litoria caerulea ) using two types of rebound tonometers, and to assess whether time of day or method of restraint affected IOP. Eighteen conscious, unrestrained, ophthalmologically normal frogs were used to measure IOP using TonoVet® and TonoLab® tonometers, at three time points during the day. In a subset of 12 frogs, IOP was measured while under manual restraint using the TonoVet. Anesthesia was induced in 9 frogs using two different concentrations of MS-222 (0.5 g/L and 2 g/L) in order to evaluate for changes in IOP with the TonoVet. Mean (± SD) IOP values for the TonoLab (16.8 ± 3.9 mm Hg) were significantly higher than TonoVet values (14.7 ± 1.6 mm Hg; P0.01). TonoVet IOP values did not significantly change with time of day. TonoLab values were significantly lower in the evening (1600-1800; 14.5 ± 3.1 mm Hg), compared with morning and midday measurements (0800-1000 and 1200-1400; 18.0 ± 3.8 mm Hg; P0.01). Manually restrained frogs had significantly lower IOP (13.4 ± 1.5 mm Hg) compared with unrestrained frogs (15.3 ± 1.2 mm Hg; P0.01). Chemical restraint did not cause significant changes in IOP. Intraocular pressure can be measured with both types of rebound tonometers in White's tree frogs, but time of day and manual restraint can affect IOP values. |
| Databáze: | OpenAIRE |
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