Reinfusion of Autogenous Ascitic Fluid Concentrated by Freezing in Patients with Intractable Ascites

Autor: Kakaru Matsuo, Shigeru Masuya, Toshinori Morikawa, Shin Chiyoda
Rok vydání: 1992
Předmět:
Zdroj: Internal Medicine. 31:325-332
ISSN: 1349-7235
0918-2918
DOI: 10.2169/internalmedicine.31.325
Popis: Eleven patients with intractable ascites were treated by intravenous reinfusion of concentrated autogenous ascitic fluid. The ascitic fluid was drained and centrifuged for removal of cells by a cell separator. Cell-free ascitic fluid was frozen in a medical freezer at -15 degrees C and thawed at room temperature. The fraction at the initial stage of melting contains a high concentration of protein and was thus collected and reinfused to the patient. In this initial fraction, the recovery rate of albumin was 42.0 +/- 9.0% and the concentration of protein was 7.1 +/- 2.4 g/dl. This frozen method is inexpensive and time saving, because it does not use a filter. Ascites was ameliorated in all patients with 1 to 19 times of reinfusion. Therefore, when renal function is not disturbed, the frozen method may be indicated for management of intractable ascites.
Databáze: OpenAIRE