Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: review of rationale and preliminary report
| Autor: | C Sacilotto, F Soldano, B Zennaro, Enrico Muzzi, R Visentin |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Hearing loss Hearing Loss Sensorineural Salvage treatment Audiology Hyperbaric oxygen Preliminary report medicine Humans Retrospective Studies Salvage Therapy Hyperbaric Oxygenation medicine.diagnostic_test Pure tone business.industry Retrospective cohort study General Medicine Middle Aged Treatment Outcome Otorhinolaryngology Anesthesia Sudden sensorineural hearing loss Audiometry Pure-Tone Female medicine.symptom Audiometry business |
| Zdroj: | The Journal of Laryngology & Otology. 124 |
| ISSN: | 1748-5460 0022-2151 |
| DOI: | 10.1017/s0022215109992052 |
| Popis: | Background:The management of sudden sensorineural hearing loss has not yet been standardised. Hyperbaric oxygen therapy influences recovery from sudden sensorineural hearing loss, but the underlying mechanism is unknown and the appropriate indications and protocols undetermined.Materials and methods:Nineteen patients affected by sudden sensorineural hearing loss were treated after unsuccessful medical therapy, either in an acute or chronic setting. Pure oxygen inhalation at 2.5 atmospheres absolute pressure was administered for 90 minutes, for 30 sessions. Frequency-specific and average pure tone hearing thresholds were determined before and after hyperbaric oxygen therapy. The number of hyperbaric oxygen therapy sessions, the patient's age and any therapeutic delay were considered as quantitative variables possibly influencing outcome. Stepwise multivariate analysis was performed.Results:Salvage hyperbaric oxygen therapy appeared to improve patients' pure tone hearing thresholds, particularly at low frequencies. Positive results were more likely with increased patient age and reduced delay in receiving hyperbaric oxygen therapy.Conclusion:Hyperbaric oxygen therapy has a strong scientific rationale, and improves pure tone hearing thresholds in cases of sudden sensorineural hearing loss unresponsive to medical therapy. Further research may be able to identify those patients with sudden sensorineural hearing loss for whom hyperbaric oxygen therapy would be most cost-effective. |
| Databáze: | OpenAIRE |
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