Transradial left gastric artery embolization to treat severe obesity: A pilot study
| Autor: | Olivier F. Bertrand, Paul Poirier, Béla Merkely, Balázs Nemes, Olivier Costerousse, Charles Pirlet, Zoltán Ruzsa |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Bariatrics Percutaneous Time Factors Left gastric artery medicine.medical_treatment Pilot Projects Punctures 030204 cardiovascular system & hematology Severity of Illness Index law.invention Body Mass Index 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law medicine.artery Catheterization Peripheral Weight Loss medicine Fluoroscopy Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Embolization Obesity Particle Size medicine.diagnostic_test business.industry General Medicine Severe obesity Middle Aged Embolization Therapeutic Surgery Treatment Outcome Gastric Artery Polyvinyl Alcohol Radial Artery Feasibility Studies Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 93(3) |
| ISSN: | 1522-726X |
| Popis: | Background Bariatric surgery is currently the only effective treatment with long-lasting results to treat severe obesity. Objectives We performed a pilot study to evaluate the feasibility, safety and efficacy of percutaneous distal embolization of the left gastric artery (LGA) using a transradial approach. Methods and results We recruited seven severely obese male patients (mean age 48 ± 7 years) referred for diagnostic coronary angiography. Mean baseline weight was 160 ± 27 kg and body mass index was of 52 ± 8 kg/m2 . We successfully injected 300-500 μm polyvinyl alcohol particles using 5Fr catheters and all distal LGA were occluded at the end of procedures. Mean procedure duration was 24 ± 13 min and mean fluoroscopy time was 10 ± 5 min. Six patients reported mild transient epigastric discomfort, which resolved with proton pump inhibitors. At 2 months, the average weight loss was of 7 ± 6 kg (median loss: -10 kg [-2, -11]), 6 ± 12 kg (median loss: -9 kg [-16, +4]) at 6 months and 13 ± 17 kg (median loss: -11 kg [0, -25]) up to 12 months after index procedures. Conclusion Percutaneous transradial LGA embolization appears to be a promising technique to reduce the obesity burden. Randomized trials are required to further delineate the risk/benefit ratio, potential clinical indications and long term results. |
| Databáze: | OpenAIRE |
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