Metal influence on metallothionein synthesis in the hydrothermal vent mussel Bathymodiolus thermophilus
| Autor: | Marc Laulier, Marie-Véronique Demattei, Paco Bustamante, Yann Hardivillier, Richard P. Cosson, Françoise Denis |
|---|---|
| Přispěvatelé: | Centre de Recherche sur les Ecosystèmes Littoraux Anthropisés (CRELA), Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de La Rochelle (ULR)-Centre National de la Recherche Scientifique (CNRS), Richard, Evelyne, Laboratoire de Biologie et Génétique Evolutive (LBGE), Le Mans Université (UM), Laboratoire d'Etude des Parasites Génétiques (LEPG), Université de Tours (UT), LIttoral ENvironnement et Sociétés - UMRi 7266 (LIENSs), Université de La Rochelle (ULR)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biologie Marine, Université de Nantes (UN)-ISOMer, Biologie des organismes marins et écosystèmes (BOME), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Muséum national d'Histoire naturelle (MNHN), Université de Tours |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Gills
Gill MESH: Fatal Outcome Physiology Health Toxicology and Mutagenesis Bathymodiolus MESH: Leukocidins MESH: Base Sequence 010501 environmental sciences Toxicology 01 natural sciences Biochemistry MESH: Staphylococcus aureus [SDV.EE.ECO] Life Sciences [q-bio]/Ecology environment/Ecosystems Metallothionein MESH: Animals Bathymodiolus thermophilus Mantle (mollusc) ComputingMilieux_MISCELLANEOUS 0303 health sciences MESH: Middle Aged biology Metal Ecology MESH: Pneumonia Staphylococcal General Medicine MESH: Metals Heavy MESH: Gene Expression Regulation Atmospheric Pressure MESH: Water Pollutants Chemical [SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology Hydrothermal vent animal structures Molecular Sequence Data MESH: Sequence Alignment 03 medical and health sciences [SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/Ecosystems Metals Heavy Animals [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology RNA Messenger 14. Life underwater MESH: RNA Messenger 030304 developmental biology 0105 earth and related environmental sciences MESH: Molecular Sequence Data MESH: Humans Base Sequence MESH: Mytilidae MESH: Methicillin Resistance Protein MESH: Metallothionein fungi MESH: Atmospheric Pressure DNA Cell Biology Mussel biology.organism_classification Bivalvia Hydrothermal MESH: Exotoxins Metabolism Gene Expression Regulation MESH: Bacterial Toxins Mytilidae RNA Gene expression MESH: Gills Sequence Alignment MESH: Female Water Pollutants Chemical |
| Zdroj: | Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2006, 143, pp.321-332 Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2006, 143, pp.321-332. ⟨10.1016/j.cbpc.2006.03.006⟩ Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2006, 143 (3), pp.321-32. ⟨10.1016/j.cbpc.2006.03.006⟩ |
| ISSN: | 1532-0456 |
| DOI: | 10.1016/j.cbpc.2006.03.006⟩ |
| Popis: | International audience; The present study reports on the metallothionein expression in the hydrothermal vent mussel Bathymodiolus thermophilus. Metallothioneins (MT) are proteins involved in intracellular metal regulation and conserved throughout the animal kingdom. The hydrothermal vent environment presents peculiarities (high levels of sulfides and metals, low pH, anoxia) that may have driven associated species to develop original evolutionary ways to face these extreme living conditions. Mussels were exposed to different metal solutions at the atmospheric pressure. The MT mRNA levels and MT contents were measured in gills and mantles of each exposed mussel. The intracellular metal distribution was estimated in fractions obtained after the centrifugation of tissue homogenates. A few of the tested metals (Ag, Cu, Cd, Hg and Zn) were able to significantly induce MT mRNA levels. Silver was the only one that produced a significant increase of the MT protein level in both mantle and gills. The gills always presented higher MT protein levels than the mantle did, while their MT mRNA levels were similar. Our data show that MT mRNA and MT protein levels do not follow a clear relationship in the gills and mantle of B. thermophilus and we assume that a post-transcriptional control occurs in these mussels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect