Age-Related Differences in Non-Persistence with Statin Treatment in Patients after a Transient Ischaemic Attack
| Autor: | Dusan Zatko, Peter Kukumberg, Jan Luha, Petra Matalova, Beata Havelkova, Jan Murin, Tomas Tesar, Martin Wawruch, Sona Wimmerova, Rashmi Shah, Gejza Wimmer |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Hypercholesterolemia Medication Adherence Persistence (computer science) Cohort Studies 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Diabetes mellitus Internal medicine Diabetes Mellitus Humans Medicine Pharmacology (medical) 030212 general & internal medicine Aged Proportional Hazards Models Aged 80 and over Polypharmacy business.industry Proportional hazards model Hazard ratio General Medicine Middle Aged medicine.disease Ischemic Attack Transient Cohort Physical therapy Female Hydroxymethylglutaryl-CoA Reductase Inhibitors business 030217 neurology & neurosurgery Cohort study |
| Zdroj: | Clinical Drug Investigation. 37:1047-1054 |
| ISSN: | 1179-1918 1173-2563 |
| Popis: | Non-persistence with secondary preventive measures, including medications such as statins, adversely affects the prospects of successful outcomes. This study was aimed at evaluating non-persistence with statin therapy in cohorts of young and elderly patients after a transient ischaemic attack (TIA) and identifying patient-associated characteristics that influence the risk for non-persistence. The study cohorts included 797 adult patients who were initiated on statin therapy following a TIA diagnosis between 1 January 2010 and 31 December 2010. Patients were followed up for 3 years and those with a treatment gap of at least a 6-month period were considered ‘non-persistent’. In order to identify any age-related differences, all analyses were conducted in the entire study cohort (n = 797) as well as separately in the ‘younger’ (aged |
| Databáze: | OpenAIRE |
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