Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
| Autor: | Felipe Suárez H, Daniela Urrutia E, Felipe Canales P, Camila Gutiérrez O |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
030203 arthritis & rheumatology
medicine.medical_specialty Neuromyelitis optica Cyclophosphamide business.industry Multiple sclerosis Neuromyelitis Optica General Medicine medicine.disease Dermatology 03 medical and health sciences 0302 clinical medicine Aquaporin 4 Methylprednisolone Immunology medicine Demyelinating disease Optic nerve Lupus Erythematosus Systemic Rituximab business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Revista médica de Chile v.144 n.9 2016 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| DOI: | 10.4067/s0034-98872016000900020 |
| Popis: | Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on immunosuppressive drugs. Immunomodulators are contraindicated. We report a previously healthy 35 years old man, presenting with NMO concomitantly with a systemic lupus erythematosus. His evolution was torpid with three outbreaks in the 10 months after the diagnosis, requiring a first-line therapy with methylprednisolone and cyclophosphamide and then a second-line therapy with rituximab. |
| Databáze: | OpenAIRE |
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