Naloxone use among overdose prevention trainees in New York City: A longitudinal cohort study
| Autor: | Anne Siegler, Andrea Jakubowski, Zina Huxley-Reicher, Chloe Oliver, Robyn Jordan, Lara Maldjian, Hillary V. Kunins |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Narcotic Antagonists 030508 substance abuse Toxicology 03 medical and health sciences 0302 clinical medicine Naloxone Humans Medicine Pharmacology (medical) Longitudinal Studies Prospective Studies 030212 general & internal medicine Longitudinal cohort Psychiatry Pharmacology business.industry Public health Opioid overdose medicine.disease Analgesics Opioid Needle-Exchange Programs Psychiatry and Mental health Opioid Emergency medicine Cohort New York City Observational study Drug Overdose Opiate 0305 other medical science business medicine.drug |
| Zdroj: | Drug and Alcohol Dependence. 179:124-130 |
| ISSN: | 0376-8716 |
| DOI: | 10.1016/j.drugalcdep.2017.06.029 |
| Popis: | Background Providing naloxone to laypersons who are likely to witness an opioid overdose is now a widespread public health response to the national opioid overdose epidemic. Estimating the proportion of individuals who use naloxone can define its potential impact to reduce overdose deaths at a population level. We determined the proportion of study participants who used naloxone within 12 months following training and factors associated with witnessing overdose and naloxone use. Methods We conducted a prospective, observational study of individuals completing overdose prevention training (OPT) between June and September 2013. Participants were recruited from New York City's six largest overdose prevention programs, all operated by syringe exchange programs. Questionnaires were administered at four time points over 12 months. Main outcomes were witnessing or experiencing overdose, and naloxone administration. Results Of 675 individuals completing OPT, 429 (64%) were approached and 351 (52%) were enrolled. Overall, 299 (85%) study participants completed at least one follow-up survey; 128 (36%) witnessed at least one overdose. Of 312 witnessed opioid overdoses, naloxone was administered in 241 events (77%); 188 (60%) by the OPT study participant. Eighty-six (25%) study participants administered naloxone at least once. Over one third of study participants (30, 35%) used naloxone 6 or more months after training. Conclusions Witnessing an overdose and naloxone use was common among this study cohort of OPT trainees. Training individuals at high risk for witnessing overdoses may reduce opioid overdose mortality at a population level if sufficient numbers of potential responders are equipped with naloxone. |
| Databáze: | OpenAIRE |
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