High genetic diversity of measles virus, World Health Organization European region, 2005-2006
| Autor: | Annette Mankertz, M Muscat, María del Mar Mosquera, Claude P. Muller, Galina V. Semeiko, Alma Robo, Elena Samoilovich, Andreas Mentis, Claudia Fortuna, Nazim Shugayev, Sergey V. Shulga, Elena N. Lopareva, Yair Aboudy, Bogumila Litwinska, Diane Waku-Kouomou, Helena Rebelo de Andrade, Juan Emilio Echevarría, Mirsada Hukić, Inna Sarv, Jacques R. Kremer, Irina V. Demchyshyna, Fabio Magurano, Sabine Santibanez, Zefira Mihneva, Lasse Vinner, Emilia Lupulescu, Ljubov S. Nekrasova, T. Fabian Wild, Kevin E. Brown, Kari Johansen, M.A. Naumova, David Brown, Mick N. Mulders, Li Jin, Elmira S. Utegenova, Rob van Binnendijk, David F. Featherstone, Paul A. Rota, Sultana Djemileva, Jean-Luc Richard, Jasminka Nedeljkovic |
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| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
Genotype Epidemiology viruses Zoology lcsh:Medicine World Health Organization Measles molecular epidemiology Virus years 2005-2006 lcsh:Infectious and parasitic diseases Measles virus medicine Humans lcsh:RC109-216 Phylogeny Genetic diversity research biology Molecular epidemiology Transmission (medicine) lcsh:R Outbreak Genetic Variation biology.organism_classification medicine.disease Virology Vaccination Europe Infectious Diseases measles virus WHO European Region |
| Zdroj: | Emerging Infectious Diseases Scopus-Elsevier Emerging Infectious Diseases, Vol 14, Iss 1, Pp 107-114 (2008) |
| Popis: | Importation of viruses from other continents caused prolonged circulation and large outbreaks in the WHO European Region. During 2005–2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities. |
| Databáze: | OpenAIRE |
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