Sex Difference in Coronary Artery Bypass Grafting: Preoperative Profile and Early Outcome
| Autor: | Joost F. ter Woorst, Mohamed A. Soliman-Hamad, Albert H.M. van Straten, Saskia Houterman |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Bypass grafting Psychological intervention Coronary Artery Disease 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Postoperative Complications 030202 anesthesiology Risk Factors Diabetes mellitus Internal medicine Preoperative Care medicine Risk of mortality Humans Hospital Mortality Coronary Artery Bypass Aged Netherlands Retrospective Studies Aged 80 and over Creatinine Sex Characteristics business.industry Middle Aged medicine.disease Anesthesiology and Pain Medicine medicine.anatomical_structure Treatment Outcome chemistry Female Underweight medicine.symptom Cardiology and Cardiovascular Medicine business Body mass index Artery |
| Zdroj: | Journal of cardiothoracic and vascular anesthesia. 33(10) |
| ISSN: | 1532-8422 |
| Popis: | Objective According to the available risk-stratification systems, women have a higher risk of mortality than men after coronary artery bypass grafting (CABG). In this study, the authors investigated the authors’ CABG database to trace factors contributing to this difference in outcome between sexes. Design A retrospective patient record study. Setting This single-center study was performed at the Catharina Hospital in Eindhoven, the Netherlands. Participants The study comprised 17,919 patients, of whom 4,016 (22.4%) were women and 13,903 (77.6%) were men. Interventions Coronary artery bypass grafting was performed between January 1998 and July 2016. Measurements and Main Results Early mortality was significantly higher in women than in men (2.7% v 1.9%; p = 0.001). Regarding the baseline characteristics, women were older and had a lower hemoglobin level and a lower creatinine level than men. Women more often had hypertension, diabetes, underweight (body mass index [BMI] 30 kg/m2). The mean number of grafts per patient was less in women than in men (3.2 ± 1.1 v 3.5 ± 1.1; p Conclusion The preoperative patient profile is significantly different between men and women undergoing CABG. The predictive value of well-known risk factors for early mortality is different between the 2 sexes. |
| Databáze: | OpenAIRE |
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