Increased serum asymmetric dimethylarginine level is an independent predictor of contrast-induced nephropathy
| Autor: | Mehmet Gungor Kaya, Ozgur Gunebakmaz, Mahmut Akpek, Ali Ergin, Esen Tanrıkulu, Mustafa Duran, Ekrem Karakaya |
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| Rok vydání: | 2013 |
| Předmět: |
Male
lcsh:Internal medicine lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty asymmetric dimethylarginine Contrast-induced nephropathy lcsh:Medicine Contrast Media Arginine Coronary Angiography Gastroenterology coronary angiography creatinine/blood Angina Pectoris Nephropathy chemistry.chemical_compound Predictive Value of Tests contrast media/adverse effects Internal medicine Diabetes mellitus medicine Humans lcsh:RC31-1245 Aged Creatinine Framingham Risk Score business.industry lcsh:R Odds ratio Middle Aged medicine.disease Confidence interval ROC Curve chemistry lcsh:RC666-701 Cardiology Female Kidney Diseases Cardiology and Cardiovascular Medicine business Asymmetric dimethylarginine |
| Zdroj: | Türk Kardiyoloji Derneği Arşivi, Vol 41, Iss 7, Pp 581-588 (2013) |
| ISSN: | 1016-5169 |
| DOI: | 10.5543/tkda.2013.88403 |
| Popis: | Objectives: The aim of our study was to evaluate whether serum asymmetric dimethylarginine (ADMA) level is an independent predictor of contrast-induced nephropathy (CIN). Study design: The study involved 90 consecutive patients with stable angina pectoris who underwent coronary angiography and ventriculography. Baseline serum creatinine (SCr) levels ranged between ≥1.2 and 124.7 ng/ml had 80% sensitivity and 76% specificity in predicting the development of CIN. In addition, we found a positive correlation between SCr change and serum ADMA level (p=0.001, r=0.35). Conclusion: Our study demonstrates that increased serum ADMA level is an independent predictor of CIN. |
| Databáze: | OpenAIRE |
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