Metastatic uterine tumor resembling ovarian sex cord tumor: A case report and review of the literature
| Autor: | Ardeshir Hakam, S.E. Robertson, Mian M.K. Shahzad, Michelle Kuznicki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
medicine.medical_specialty Gonadal cord Adjuvant chemotherapy medicine.medical_treatment Case Report lcsh:Gynecology and obstetrics lcsh:RC254-282 Metastasis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Chemotherapy Epithelial ovarian cancer lcsh:RG1-991 030219 obstetrics & reproductive medicine business.industry Ovarian sex cord tumors Uterine tumor resembling ovarian sex cord tumor Obstetrics and Gynecology Metastasis Uterine cancer Abdominal distension medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Uterine Tumor 030220 oncology & carcinogenesis medicine.symptom business |
| Zdroj: | Gynecologic Oncology Reports, Vol 22, Iss C, Pp 64-68 (2017) Gynecologic Oncology Reports |
| ISSN: | 2352-5789 |
| Popis: | Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare and commonly characterized as benign tumors, with infrequent reports of metastasis and recurrence. Treatment recommendations have not been well established, particularly for more advanced cases. We present the first reported death from a metastatic UTROSCT, summarize the available literature, and describe characteristics common to UTROSCTs with aggressive features. In this case, a 49-year-old woman presented with abdominal distension and pain; initial imaging and diagnostic workup suggested metastatic epithelial ovarian cancer to be the cause. The patient subsequently underwent neoadjuvant chemotherapy followed by optimal cytoreductive surgery and adjuvant chemotherapy. Final pathology revealed UTROSCT with omental and peritoneal metastases. She then underwent adjuvant chemotherapy with subsequent recurrence and died 15 months after her initial diagnosis. Our analysis of this case and the available literature led us to identify pathologic risk factors that may help predict aggressive UTROSCT behavior. Highlights • Uterine tumors resembling ovarian sex cord tumors are rare and generally considered benign. • Few aggressive/metastatic cases have been reported, and we report on the first death from this disease. • Analysis of the literature allowed for identification of potential pathologic risk factors of aggressive disease. • Better identifying these risk factors could help guide treatment recommendations for this tumor type. |
| Databáze: | OpenAIRE |
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