Predictive Value of School-Aged Children's Schistosomiasis Prevalence and Egg Intensity for Other Age Groups in Western Kenya
Autor: | W. Evan Secor, Bernard Abudho, Pauline N. M. Mwinzi, Martin Omedo, Susan P. Montgomery, Geoffrey Muchiri, Diana M. S. Karanja, Ryan E. Wiegand |
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Rok vydání: | 2015 |
Předmět: |
Adult
Kenya Schistosomiasis Severity of Illness Index Feces Young Adult Age groups Virology parasitic diseases Severity of illness Prevalence Animals Humans Medicine Young adult Child Mass drug administration Parasite Egg Count biology business.industry Age Factors Articles Schistosoma mansoni Middle Aged biology.organism_classification medicine.disease Health Surveys Predictive value Schistosomiasis mansoni Infectious Diseases Child Preschool Immunology Parasitology business Demography |
Zdroj: | The American Journal of Tropical Medicine and Hygiene. 93:1311-1317 |
ISSN: | 1476-1645 0002-9637 |
DOI: | 10.4269/ajtmh.15-0467 |
Popis: | World Health Organization recommendations for the timing and target population for mass drug administration (MDA) for schistosomiasis are based on the prevalence of infection in school children within a given community. In a large study comparing MDA approaches for Schistosoma mansoni control, we evaluated whether prevalence of infection and egg burdens in 9- to 12-year-old students reflected infection levels in young children and adults in the same community. Cross-sectional surveys of preadolescents (9–12 years old) were compared with those of first year students (5–8 years old) in 225 villages and adults (20–55 years old) in 150 villages along the Kenyan shores of Lake Victoria. Village schistosomiasis prevalence and intensity levels in preadolescents strongly correlated (P < 0.0001) with prevalence and infection intensity for other age groups in the community. Our findings suggest that S. mansoni prevalence and intensity among 9- to 12-year-olds are valid for community sampling purposes in mapping for MDAs. |
Databáze: | OpenAIRE |
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