Multivariate Association of Child Depression and Anxiety With Asthma Outcomes
| Autor: | Alyson Nakamura, Tressa Lloyd, Josseline Lopez, Shane Tipton, Raymond Chankalal, E. Sherwood Brown, Ray J. Pak, Quratulain Humayun, Alexandra Kulikova, Beatrice L. Wood, Bruce D. Miller, Donna Persaud, Heather K. Lehman, Dave A. Khan, Zena Patel, Elena I. Ivleva, M. Seth Owitz, Savitoj Kaur, Anna Antony, Michael S. Adragna, Karen Allen, Jasmine Tiro |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Multivariate statistics Anxiety Asthma management Article 03 medical and health sciences 0302 clinical medicine Quality of life immune system diseases Asthma control medicine Humans Immunology and Allergy 030212 general & internal medicine Child Association (psychology) Biological Psychiatry Depression (differential diagnoses) Asthma Depression business.industry medicine.disease Anxiety Disorders respiratory tract diseases 030228 respiratory system Quality of Life Female medicine.symptom business Clinical psychology |
| Zdroj: | J Allergy Clin Immunol Pract |
| ISSN: | 0006-3223 |
| Popis: | BACKGROUND: Pediatric asthma is associated with increased health services utilization, missed school days and diminished quality of life. Children with asthma also report more frequent depressive and anxiety symptoms than non-asthmatic children, which may further worsen asthma outcomes. OBJECTIVE: The current study investigated the relationship between depressive and anxiety symptoms and four asthma outcomes (asthma control, asthma severity, lung function, and asthma-related quality of life) in children (N = 205) with moderate-to-severe persistent asthma. METHODS: The data were analyzed using a canonical correlation analysis (CCA), a multivariate framework that allows examination of all variables of interest in the same model. RESULTS: We found a statistically significant relationship between symptoms of depression and anxiety and asthma outcomes (1 − Λ = .372, p < .001). A large effect size suggests that 37.2% of variance is shared between depression and anxiety symptoms and four asthma outcomes (particularly asthma control and asthma-related quality of life) in the overall sample. Among girls (vs. boys), asthma control (measured by ACT) emerged as a stronger contributor to asthma outcomes compared to boys. CONCLUSIONS: These results suggest that psychiatric symptoms, especially anxiety, are associated with poor asthma-related quality of life, and more negative perception of asthma control in girls compared to boys (with no observed sex difference in physiological lung function). Clinicians should consider incorporating questions about psychiatric symptoms as part of routine asthma management, and focus patient education on unique differences in which boys and girls perceive their asthma symptoms. |
| Databáze: | OpenAIRE |
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