The Role of Post-treatment FDG-PET/CT Scanning after the First-line Chemotherapy in Predicting Prognosis in Patients with Hodgkin Disease and High-grade Non-Hodgkin Lymphoma: A Comparative Study with Clinical Prognostic Risk Scoring Data

Autor: Ezgi Başak ERDOĞAN, Şebnem GÜNER, Kerim SÖNMEZOĞLU
Přispěvatelé: ERDOĞAN, EZGİ BAŞAK, Güner, Şebnem
Rok vydání: 2022
Předmět:
Zdroj: Bezmialem Science. 10:264-273
ISSN: 2148-2373
DOI: 10.14235/bas.galenos.2021.5981
Popis: Objective: We aimed to evaluate the role of fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) performed after the first-line therapy in predicting prognosis of lymphomas and compare the results with the pretreatment prognostic risk scoring (PRS) indices. Methods: One hundred three patients with histopathologically confirmed Hodgkin (HD) and high-grade non-Hodgkin lymphoma (NH L) were included in the study. All patients received FDG-PET/ CT imaging after the end of primary treatment. After intraveneus application of FDG, whole body PET/CT horn the upper thigh to the vertex was performed. Results: The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of post-treatment FDG-PET/CT imaging in predicting remission status were - 3.6%, 91.6%, 88%, 66.6%, and 94.0%, respectively. Those values were 63.0%, 62.0%. 62.0%, 27%, and 88.0% respectively, for pretreatment clinical risk scoring (p
Databáze: OpenAIRE
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