Observation or resection of pancreatic intraductal papillary mucinous neoplasm: An ongoing tug of war
Autor: | Kjetil Søreide, Jan Rune Aunan, Nigel B. Jamieson |
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Rok vydání: | 2019 |
Předmět: |
Opinion Review
medicine.medical_specialty Surveillance Intraductal papillary mucinous neoplasm Neoplasia business.industry Risk of malignancy Tug of war General surgery Gastroenterology Pancreatic cancer Pancreatic cyst Biomarker medicine.disease Resection medicine.anatomical_structure Oncology Diagnosis Mutation medicine Pancreas business |
Zdroj: | World Journal of Gastrointestinal Oncology |
ISSN: | 1948-5204 |
Popis: | An increasing number of patients are being referred to pancreatic centres around the world due to often incidentally discovered cystic neoplasms of the pancreas. The evaluation and management of pancreatic cystic neoplasms is a controversial topic and with existing guidelines based on a lack of strong evidence there is discordance between centres and guidelines with regard to when to offer surgery and when to favour surveillance. The frequency, duration and modality of surveillance is also controversial as this is resource-consuming and must be balanced against the perceived benefits and risks involved. While there is consensus that the risk of malignancy should be balanced against the life-expectancy and comorbidities, the indications for surgery and surveillance strategies vary among the guidelines. Thus, the tug of war between surveillance or resection continues. Here we discuss the recommendations from guidelines with further accumulating data and emerging reports on intraductal papillary mucinous neoplasm in the literature. publishedVersion |
Databáze: | OpenAIRE |
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