99mTc-Ciprofloxacin planar and tomographic imaging for the diagnosis of infection in the postoperative spine: experience in 48 patients
| Autor: | Christophe Van de Wiele, Koen Van Laere, Frederic De Winter, F. Gemmel, Olivier De Winter, Bart Poffijn, Rudi Dierckx |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Planar Imaging Adolescent Scintigraphy Sensitivity and Specificity Ciprofloxacin White blood cell medicine Humans Surgical Wound Infection Radiology Nuclear Medicine and imaging Spondylitis Aged Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Reproducibility of Results Organotechnetium Compounds General Medicine Middle Aged medicine.disease medicine.anatomical_structure Spinal Cord Positron emission tomography Orthopedic surgery Female Tomography Radiology Radiopharmaceuticals business Nuclear medicine medicine.drug |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 31:233-239 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-003-1349-0 |
| Popis: | The non-invasive assessment of postoperative spinal infections can pose a substantial diagnostic challenge, especially in the presence of orthopaedic devices. Whereas white blood cell scanning is of limited use in the spine, the low normal bone marrow uptake of technetium-99m ciprofloxacin combined with its claimed bacterial specificity makes it theoretically an ideal candidate for the evaluation of postoperative spinal infections. This study aimed to evaluate 99mTc-ciprofloxacin planar and single-photon emission tomography (SPET) imaging in relation to microbiological and clinical diagnosis in the postoperative spine. Planar imaging was performed at 1, 3 and 24 h and SPET was performed at 3 h post injection of 370 MBq 99mTc-ciprofloxacin. Images were scored by two independent certified nuclear medicine physicians, blinded to the final diagnosis. Within the 48 patients, there were 13 deep infections. Sensitivity, specificity and accuracy at visual scoring were respectively 54%, 71% and 67% (1 h), 62%, 77% and 73% (3 h), 42%, 91% and 77% (24 h) for planar imaging and 100%, 74% and 81% for SPET. When recently operated patients ( |
| Databáze: | OpenAIRE |
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