Nucleotide sequences of the trailer, nucleocapsid protein gene and intergenic regions of Newcastle disease virus strain Beaudette C and completion of the entire genome sequence

Autor:	Siba K. Samal, Sateesh Krishnamurthy
Rok vydání:	1998
Předmět:	Genetics Whole genome sequencing Base Sequence biology Strain (chemistry) Molecular Sequence Data Newcastle disease virus Virulence Genome Viral biology.organism_classification Newcastle disease Virology Virus Intergenic region RNA Viral Avulavirus Nucleocapsid Gene
Zdroj:	Journal of General Virology. 79:2419-2424
ISSN:	1465-2099 0022-1317
Popis:	The nucleotide sequences of the nucleocapsid protein (NP) gene, the intergenic regions in the nucleocapsid protein (NP)-phosphoprotein (P), P-matrix protein (M) and M-fusion glycoprotein gene junctions and the trailer region of a virulent Newcastle disease virus (NDV) strain Beaudette C were determined. The NP gene is 1747 nt long and encodes a protein of 489 amino acids. Each of the intergenic sequences determined is 1 nt long and, including the previously published intergenic sequences, the gene junction sequences varied in length from 1-47 nt and lacked any sequence identity. The 5' trailer region is 113 nt in length. Comparison of the sequences of the terminal leader and trailer regions of Beaudette C strain with those of nonvirulent strain B1 showed a high level of conservation, indicating the likelihood of these elements not being a factor in virulence. Together with previously published data, this report completes the sequence of the 15,186 nt genomic RNA of NDV strain Beaudette C.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a4992472cf9f03068ce40836a878b2 https://doi.org/10.1099/0022-1317-79-10-2419 Zobrazit plný text záznamu