Association between mean platelet volume and disease severity in patients with psoriasis and psoriatic arthritis
| Autor: | Meliha Merve Hiz, Zerrin Ogretmen, Selda Işik, Ayla Akbal, Sibel Oymak, Hatice Reşorlu, Sevilay Kiliç |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
lcsh:Internal medicine psoriasis severity score Dermatology Disease Gastroenterology 030207 dermatology & venereal diseases 03 medical and health sciences Psoriatic arthritis 0302 clinical medicine Disease severity Internal medicine Psoriasis lcsh:Dermatology Immunology and Allergy Medicine Platelet In patient Mean platelet volume Prospective cohort study lcsh:RC31-1245 030203 arthritis & rheumatology psoriatic arthritis Original Paper mean platelet volume business.industry psoriasis lcsh:RL1-803 medicine.disease business |
| Zdroj: | Advances in Dermatology and Allergology, Vol 34, Iss 2, Pp 126-130 (2017) Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| ISSN: | 2299-0046 |
| Popis: | Introduction: Mean platelet volume (MPV) is an important marker that shows the activation and function of the platelets, which is effective in the inflammatory diseases. Aim : To show the relationship between MPV and the development of psoriatic arthritis (PA) in patients with psoriasis vulgaris (PV) and the correlation between MPV and psoriasis severity score (PASI). Material and methods : Our study included 116 patients with psoriatic arthritis (68 female, 48 male) and 41 patients in the psoriasis group (19 female, 22 male) and 90 subjects in the control group (55 female, 35 male). The demographic data of the patients, duration of disease, PASI, the nature of the disease were evaluated retrospectively. Results : Mean platelet volume levels of both the PV group (8.79 ±0.86 fl) and the PA group (9.18 ±1.26 fl) were significantly higher compared to the control group (8.42 ±0.74 fl). There was a weak statistically positive correlation between the PASI and the MPV according to the correlation analysis (r = 0.165; p = 0.046). Conclusions : Our results show that MPV may be helpful as an indicator of the clinical course of PV and PA. In this regard, that study should be supported by prospective studies to find strong correlations. |
| Databáze: | OpenAIRE |
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