Is e-cigarette use in non-smoking young adults associated with later smoking?:A systematic review and meta-analysis
| Autor: | Jasmine N. Khouja, Sarah E Peters, Steph Suddell, Marcus R. Munafò, Amy E Taylor |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Health (social science) media_common.quotation_subject Review Cochrane Library 01 natural sciences Nicotine 03 medical and health sciences 0302 clinical medicine Medicine 030212 general & internal medicine 0101 mathematics Young adult Psychiatry Association (psychology) media_common business.industry Mechanism (biology) Addiction 010102 general mathematics Tobacco and Alcohol Public Health Environmental and Occupational Health Odds ratio Random effects model Data extraction Meta-analysis co-substance use Physical and Mental Health addiction business electronic nicotine delivery devices Clinical psychology medicine.drug Bristol Population Health Science Institute |
| Zdroj: | Khouja, J, Suddell, S F, Peters, S E, Taylor, A E & Munafò, M R 2020, ' Is e-cigarette use in non-smoking young adults associated with later smoking? A systematic review and meta-analysis ', Tobacco Control . https://doi.org/10.1136/tobaccocontrol-2019-055433 Tobacco Control |
| Popis: | ObjectiveThe aim of this review was to investigate whether e-cigarette use compared to non-use in young non-smokers is associated with subsequent cigarette smoking.Data sourcesPubMed, Embase, Web of Science, Wiley Cochrane Library databases, and the 2018 Society for Research on Nicotine and Tobacco and Society for Behavioural Medicine conference abstracts.Study selectionAll studies of young people (up to age 30 years) with a measure of e-cigarette use prior to smoking and an outcome measure of smoking where an odds ratio could be calculated were included (excluding reviews and animal studies).Data ExtractionIndependent extraction was completed by multiple authors using a pre-prepared extraction form.Data synthesisOf 9,199 results, 17 studies were included in the meta-analysis. There was strong evidence for an association between e-cigarette use among non-smokers and later smoking (OR 4.59, 95% CI 3.60 to 5.85) when the results were meta-analysed in a random effects model. However, there was high heterogeneity (I2 = 88%).ConclusionsWhilst the association between e-cigarette use among non-smokers and subsequent smoking appears strong, the available evidence is limited by the reliance on self-report measures of smoking history without biochemical verification. None of the studies included negative controls which would provide stronger evidence for whether the association may be causal. Much of the evidence also failed to consider the nicotine content of e-liquids used by non-smokers meaning it is difficult to make conclusions about whether nicotine is the mechanism driving this association. |
| Databáze: | OpenAIRE |
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