A Saudi G6PD Deficient Girl Died with Pediatric Multisystem Inflammatory Syndrome-COVID-19
| Autor: | Abdulaziz K. AlHassan, Fatima H. Alkhalifa, Sameer Y. Al-Abdi, Fatimah T. Al-Khars, Sami J. Alkhwaitem, Maryam A. Al-Aamri, Ali M. Al Aithan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
education.field_of_study
Pediatrics medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Coronavirus disease 2019 (COVID-19) business.industry Inflammatory response media_common.quotation_subject Population nutritional and metabolic diseases hemic and lymphatic diseases parasitic diseases Large study Medicine Girl business education media_common |
| DOI: | 10.1101/2020.07.08.20137497 |
| Popis: | Reports on pediatric multisystem inflammatory syndrome (PMIS) temporally related to coronavirus disease 2019 (COVID-19) are increasing. African and Afro-Caribbean children constituted about 37% of the cases in these reports. Although glucose-6-phosphatase dehydrogenase (G6PD) deficiency is common among this population, the G6PD status of these cases has not been reported. We report the first case of PMIS related to COVID-19 from Saudi Arabia. This case was a Saudi G6PD deficient girl who died with PMIS related to COVID-19. G6PD deficiency induces redox imbalance and exaggerates the inflammatory response; thus, it might contribute to the development or the grave outcome of our case. We urgently need to assess the association between G6PD deficiency and COVID-19 in a large study as the G6PD deficiency may be a useful predictor for the progression of the COVID-19. |
| Databáze: | OpenAIRE |
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