Fasting glucose in the first trimester: An initial approach to diagnosis of gestational diabetes
| Autor: | Gabriela Castillo Carbajal, Beatriz Torres Moreno, Teresa López del Val, Concepción García Lacalle, Victoria Alcázar Lázaro, Beatriz Alameda Fernandez |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty endocrine system diseases 030209 endocrinology & metabolism Physical exercise Sensitivity and Specificity Fasting glucose 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Fetal macrosomia Humans 030212 general & internal medicine Retrospective Studies Medical treatment Obstetrics business.industry Retrospective cohort study Fasting Glucose Tolerance Test medicine.disease female genital diseases and pregnancy complications Gestational diabetes First trimester Diabetes Gestational Pregnancy Trimester First Female business |
| Zdroj: | Endocrinologia, diabetes y nutricion. 66(1) |
| ISSN: | 2530-0180 |
| Popis: | OBJECTIVES To establish whether fasting glucose levels in the first trimester (FGFT)of pregnancy ≥ 92 mg/dL (5.1 mmol/L) (FGFT) anticipate the occurrence of maternal-fetal complications of gestational diabetes mellitus. To assess whether FGFT can replace diagnosis of GDM using the classical two-step oral glucose tolerance test (OGTT). METHODS A retrospective study of 1425 pregnancies with FGFT and O'Sullivan Test (OST) and/or OGTT according to OST results in the second trimester. FGFT sensitivity and specificity were assessed as compared to the conventional diagnosis of GDM. The relationship between maternal-fetal complications and FGFT was assessed in the total group and after excluding mothers who received specific medical treatment for GDM. RESULTS Sensitivity and specificity of FGFT levels ≥ 92mg/dL were 46.4% and 88.8% as compared to diagnosis of GDM using Carpenter and Coustan criteria. In the total group, a statistically significant relationship was found between FGFT levels ≥ 92 mg/dL and newborn weight (3228±86 versus 3123±31g; P |
| Databáze: | OpenAIRE |
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