Experimental confirmation of the promising selective use of 'green' laser radiation for photothermolysis of hemoglobin-containing tissues
| Autor: | Natalia Stankova, Maria Remennicova, G. P. Kuzmin, Ella Gasanova, Natalia Gorbatova, O. V. Tikhonevich, A. A. Sirotkin, Alexander Tertychny, Sergei Zolotov |
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| Rok vydání: | 2020 |
| Předmět: |
Materials science
Light Swine Population Dermatology Absorption (skin) Radiation law.invention 030207 dermatology & venereal diseases 03 medical and health sciences Hemoglobins 0302 clinical medicine law Animals Selective photothermolysis education Skin education.field_of_study Green laser Lasers 030206 dentistry Laser Radiation effect Swine Miniature Surgery Hemoglobin Biomedical engineering |
| Zdroj: | Lasers in medical science. 37(1) |
| ISSN: | 1435-604X |
| Popis: | To date, the problem of treating pathological subepithelial capillary structures, in particular, capillary angiodysplasia of the skin, remains. One of the promising methods for its elimination is photothermolysis by laser radiation of the yellow-green spectral range due to the selective absorption of blood by hemoglobin in blood vessels and, subsequently, their sclerosis and regression. In experimental work in vitro on model objects, chilled liver and skin samples from minipigs of the Svetlogorsk population, a comparison was made based on morphological studies of the results of the green laser radiation effect with a wavelength of 525 nm on these objects. In the case of a combined object (the liver under the skin), the green laser radiation that is little absorbed by the skin passes through it, which provides an effect on the underlying liver, where more pronounced thermal changes are formed compared to the skin. The results of the experimental study confirmed the selectivity of the laser radiation effect with a wavelength of 525 nm on hemoglobin-containing tissues. This fact is promising for selective photothermolysis of pathological subepithelial capillary structures, which will ensure the precision of treatment with minimal damage to skin tissues. |
| Databáze: | OpenAIRE |
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