Cerebrospinal fluid and arterial lactate, pyruvate and acid-base balance in patients with intracranial hemorrhages
| Autor: | Masatoshi Fujishima, Teruo Omae, Takenori Yamaguchi, Jun-ichiro Choki, Tomei Sugi |
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| Rok vydání: | 1975 |
| Předmět: |
Adult
Male Subarachnoid hemorrhage Intracranial Pressure Bicarbonate Partial Pressure Acid–base homeostasis Acid-Base Imbalance chemistry.chemical_compound Cerebrospinal fluid Hyperventilation medicine Humans Pyruvates Intracranial pressure Aged Cerebral Hemorrhage Advanced and Specialized Nursing business.industry Carbon Dioxide Middle Aged medicine.disease Prognosis Oxygen Bicarbonates chemistry Anesthesia Lactates Arterial blood Female Neurology (clinical) medicine.symptom Cardiology and Cardiovascular Medicine business Acid–base imbalance |
| Zdroj: | Stroke. 6(6) |
| ISSN: | 0039-2499 |
| Popis: | Lactate and pyruvate concentrations and acid-base balance in cerebrospinal fluid (CSF) and arterial blood were determined in patients with intracranial hemorrhages (28 subarachnoid hemorrhages and 15 intracerebral hemorrhages). A greater increase in CSF lactate and lactate-pyruvate ratio (L/P ratio) was observed in patients with impairment of consciousness, focal neurological deficits, poor prognosis, or CSF pressures higher than 300 mm H 2 O. A combination of CSF lactate greater than 2.5 mM per liter, L/P ratio above 20, bicarbonate less than 20.4 mEq per liter, pH below 7.276, or arterial PCO 2 below 31.5 mm Hg seems to indicate a poor prognosis from intracranial hemorrhage. The mechanism of hyperventilation in acute cerebrovascular diseases and of CSF pH regulation in acid-base disturbances was also discussed. |
| Databáze: | OpenAIRE |
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