Thymic Extension in the Superior Mediastinum in Patients with Thymic Hyperplasia: Potential Cause of False-Positive Findings on 18F-FDG PET/CT
| Autor: | Heiko Schöder, Henry W.D. Yeung, Clare S. Smith |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Thymus Gland Disease Sensitivity and Specificity Fluorodeoxyglucose F18 medicine Humans False Positive Reactions Radiology Nuclear Medicine and imaging Young adult Child Retrospective Studies PET-CT medicine.diagnostic_test business.industry Infant Newborn Mediastinum Infant Reproducibility of Results Cancer Retrospective cohort study Thymus Neoplasms General Medicine Hyperplasia Image Enhancement medicine.disease medicine.anatomical_structure Positron emission tomography Child Preschool Positron-Emission Tomography Subtraction Technique Female Radiology Radiopharmaceuticals Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | American Journal of Roentgenology. 188:1716-1721 |
| ISSN: | 1546-3141 0361-803X |
| DOI: | 10.2214/ajr.06.0552 |
| Popis: | OBJECTIVE. Although 18F-FDG PET/CT is now well established as an accurate method for the staging and restaging of various cancers, it is also well recognized that many false-positive results can occur. One such false-positive is activity within the superior extent of the thymus in the superior mediastinum.CONCLUSION. We reviewed all PET/CT examinations performed in children and young adults under the age of 20 years at our institution over a 2-month period. In 11 (12%) of the 93 examinations, activity was identified in the superior mediastinum of similar intensity to the thymus, which is consistent with activity within the superior thymic extension. In light of the increasing clinical use of FDG PET/CT for cancer imaging, it is important that nuclear medicine physicians and radiologists be aware of this phenomenon to avoid misdiagnosis or overstaging of disease. |
| Databáze: | OpenAIRE |
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