Enantioselective Catalytic Synthesis of N-alkylated Indoles
| Autor: | Tõnis Kanger, Dmitri Trubitsõn |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Indole test
Physics and Astronomy (miscellaneous) 010405 organic chemistry Chemistry lcsh:Mathematics General Mathematics asymmetric synthesis Enantioselective synthesis Alkylation lcsh:QA1-939 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis indole Chemistry (miscellaneous) Organocatalysis C-N bond formation Computer Science (miscellaneous) Surface modification organocatalysis enantioselective transition-metal catalysis |
| Zdroj: | Symmetry, Vol 12, Iss 1184, p 1184 (2020) |
| ISSN: | 2073-8994 |
| DOI: | 10.3390/sym12071184 |
| Popis: | During the past two decades, the interest in new methodologies for the synthesis of chiral N-functionalized indoles has grown rapidly. The review illustrates efficient applications of organocatalytic and organometallic strategies for the construction of chiral α-N-branched indoles. Both the direct functionalization of the indole core and indirect methods based on asymmetric N-alkylation of indolines, isatins and 4,7-dihydroindoles are discussed. |
| Databáze: | OpenAIRE |
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