The influence of chronic uremia on hepatic glycogen in the rat
Autor: | D.C. Secord, A.A. Noujaim, E.J. Sanders, A. Mannan, D.S. Silverberg, L.I. Wiebe |
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Rok vydání: | 1975 |
Předmět: |
Glycosuria
Blood Glucose Male Autolysis (biology) medicine.medical_specialty Time Factors Hepatic glycogen medicine.medical_treatment Clinical Biochemistry Chronic uremia Carbohydrate metabolism Kidney Nephrectomy chemistry.chemical_compound Internal medicine medicine Animals Decreased glycogen Uremia Glycogen General Medicine Hypoglycemia Liver Glycogen Rats Microscopy Electron Endocrinology chemistry Liver Chronic Disease medicine.symptom |
Zdroj: | Clinical biochemistry. 8(1) |
ISSN: | 0009-9120 |
Popis: | Long term maintenance of male Wistar rats following sub-total nephrectomy has been shown to alter carbohydrate metabolism. These rats frequently became hypoglycemic and concurrently demonstrated increased hepatic glycogen stores. Chemical analysis of glycogen revealed a significant increase in branching, with a concomitant decrease in glucose residues per segment. The influence of food intake and glycosuria are discussed. Decreased glycogen autolysis is attributed to increased glycogen branching in the uremic liver. |
Databáze: | OpenAIRE |
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