Opsoclonus-Myoclonus Syndrome, Neuroblastoma, and Insulin-Dependent Diabetes Mellitus in a Child: A Unique Patient
| Autor: | Glynis Price, Manoj Kanhangad, Lakshmi Nagarajan, Twinkle Ghia, Parshotam Gera, Angela J. Alessandri |
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| Rok vydání: | 2016 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Diabetic ketoacidosis medicine.medical_treatment Neuroblastoma 03 medical and health sciences 0302 clinical medicine Developmental Neuroscience 030225 pediatrics Opsoclonus myoclonus syndrome medicine Humans Thoracic Neoplasm Type 1 diabetes Opsoclonus-Myoclonus Syndrome business.industry Thoracic neuroblastoma Infant Immunotherapy Thoracic Neoplasms medicine.disease Diabetes Mellitus Type 1 Neurology Insulin dependent diabetes Pediatrics Perinatology and Child Health Immunology Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Pediatric Neurology. 55:68-70 |
| ISSN: | 0887-8994 |
| DOI: | 10.1016/j.pediatrneurol.2015.09.021 |
| Popis: | Aim We present a new and unique association of opsoclonus-myoclonus-ataxia syndrome with neuroblastoma and type 1 diabetes mellitus. Patient description This 17-month-old child presented with opsoclonus-myoclonus-ataxia syndrome. Investigations revealed a thoracic neuroblastoma. Eleven days later, she re-presented with diabetic ketoacidosis. The neuroblastoma was resected, and she was given immunotherapy. At 12 months' follow-up, her neurological signs and symptoms have significantly improved, but she continues to be insulin dependent. Discussion This child expands the clinical spectrum of autoimmune disorders associated with opsoclonus-myoclonus-ataxia syndrome. |
| Databáze: | OpenAIRE |
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