Gadolinium-DOTA enhanced MRI of painful osseous crises in children with sickle cell anemia
Autor: | M de Montalembert, G Sebag, C Glorion, D Lallemand, Robert Girot, M Wioland, V Bonnerot |
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Rok vydání: | 1994 |
Předmět: |
Adult
Male Hemolytic anemia Pathology medicine.medical_specialty Adolescent Anemia Periosteal reaction Contrast Media Pain Anemia Sickle Cell Bone Marrow Heterocyclic Compounds Organometallic Compounds medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Child Neuroradiology business.industry Ultrasound Infant Soft tissue Osteomyelitis Image Enhancement medicine.disease Magnetic Resonance Imaging Sickle cell anemia Infarction Child Preschool Acute Disease Pediatrics Perinatology and Child Health Female Radiology business Complication |
Zdroj: | Pediatric Radiology. 24:92-95 |
ISSN: | 1432-1998 0301-0449 |
DOI: | 10.1007/bf02020160 |
Popis: | In order to evaluate the role of gadolinium-DOTA enhanced MRI in the management of painful osseous crises in children with sickle cell anemia (SCA), nine children with SCA underwent MRI, bone scans and ultrasonographic studies during 11 osseous crises. Imaging findings were compared with the final diagnosis: three acute osteomyelitis (AO) and 16 acute infarcts (AI). MRI could not differentiate AO from AI. The appearance of severe AI was very misleading and was similar to the usual appearance of AO, including soft tissue changes, periosteal reaction and patterns of enhancement. Gadolinium-DOTA enhanced MRI was useful for determining the anatomic site and extent of AO or AI and for distinguishing between necrotic material, fluid collection and vascularized inflammatory tissue. It can also help to guide the aspiration of intraosseous, subperiosteal and soft tissue fluid collections. |
Databáze: | OpenAIRE |
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