Benzophenones from Hypericum carinatum
| Autor: | Gilsane Lino von Poser, Raquel Bridi, Ana Paula Machado Bernardi, A. T. Henriques, Daniela Vicentini Albring, Sergio Augusto de Loreto Bordignon, Carlos Severo Dutra-Filho, Alexandre de Barros Falcão Ferraz, Jan Schripsema |
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| Rok vydání: | 2005 |
| Předmět: |
Antioxidant
medicine.medical_treatment Campesterol Phloroglucinol Pharmaceutical Science Pharmacognosy Antioxidants Analytical Chemistry chemistry.chemical_compound Benzophenones Drug Discovery medicine Organic chemistry Pharmacology Chromatography Stigmasterol Plants Medicinal biology Dose-Response Relationship Drug Molecular Structure Organic Chemistry biology.organism_classification Plant Leaves Complementary and alternative medicine chemistry Luminescent Measurements Molecular Medicine Quercetin Hypericum Derivative (chemistry) Brazil |
| Zdroj: | Journal of natural products. 68(5) |
| ISSN: | 0163-3864 |
| Popis: | Two new benzophenones were isolated from the leaves of Hypericum carinatum. Their structures were established on the basis of 2D NMR spectroscopic analyses and mass spectrometry as cariphenone A (6-benzoyl-5,7-dihydroxy-2,2,8-trimethyl-2H-chromene) (1) and cariphenone B (8-benzoyl-5,7-dihydroxy-2,2,6-trimethyl-2H-chromene) (2). Five known compounds, the phloroglucinol derivative uliginosin B (3), 1-eicosanol, sitosterol, stigmasterol, and campesterol, were also characterized. Compounds 1-3 were evaluated for their total antioxidant capacity through a total radical-trapping parameter assay. Only compound 1 showed moderate antioxidant activity, exhibiting inhibition of chemiluminescence similar to that of quercetin at the same concentration. |
| Databáze: | OpenAIRE |
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