Mother-infant interactions and regional brain volumes in infancy:an MRI study

Autor: Sarah Lloyd-Fox, Emily Perry, Paula Busuulwa, Caroline McCusker, Vaheshta Sethna, Eileen Daly, Grainne M. McAlonan, Steven Williams, Mark H. Johnson, Maria Gudbrandsen, Kerrie P. H. Adams, Maria Kuklisova-Murgasova, Lynne Murray, Anna Blasi, Michael C. Craig, Inês Pote, Declan G. Murphy, Siying Wang
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
medicine.medical_specialty
Histology
Neurology
Infancy
Infant cerebellum
Neuroscience(all)
Psychological intervention
Maternal sensitivity
Grey matter
Infant brain structure
Developmental psychology
psyc
03 medical and health sciences
0302 clinical medicine
Child Development
Mother–infant interaction
Sex differences
medicine
Humans
0501 psychology and cognitive sciences
Mother-infant interaction
Child
Retrospective Studies
Sex Characteristics
medicine.diagnostic_test
General Neuroscience
05 social sciences
Brain
Infant
Retrospective cohort study
Magnetic resonance imaging
Human brain
Magnetic Resonance Imaging
Mother-Child Relations
medicine.anatomical_structure
Cross-Sectional Studies
Observational study
Original Article
Female
Anatomy
Psychology
030217 neurology & neurosurgery
050104 developmental & child psychology
MRI
Zdroj: Sethna, V, Pote, I, Wang, S, Gudbrandsen, M, Blasi, A, McCusker, C, Daly, E, Perry, E, Adams, K P H, Kuklisova-Murgasova, M, Busuulwa, P, Lloyd-Fox, S, Murray, L, Johnson, M H, Williams, S C R, Murphy, D G M, Craig, M C & McAlonan, G M 2017, ' Mother-infant interactions and regional brain volumes in infancy : an MRI study ', Brain structure & function, vol. 222, no. 5, pp. 2379-2388 . https://doi.org/10.1007/s00429-016-1347-1
Brain Structure & Function
ISSN: 1863-2653
1863-2661
DOI: 10.1007/s00429-016-1347-1
Popis: Background: It is generally agreed that the human brain is responsive to environmental influences, and that the male brain may be particularly sensitive to early adversity. However, this is largely based on retrospective studies of older children and adolescents exposed to extreme environments in childhood. Less is understood about how normative variations in parent-child interactions are associated with the development of the infant brain in typical settings. \ud Method: To address this, we used magnetic resonance imaging to investigate the relationship between observational measures of mother-infant interactions and regional brain volumes in a community sample of 3-6 month old infants (N=39). In addition, we examined whether this relationship differed in male and female infants. \ud Results: We found that lower maternal sensitivity was correlated with smaller subcortical grey matter volumes in the whole sample, and that this was similar in both sexes. However, male infants who showed greater levels of positive communication and engagement during early interactions had smaller cerebellar volumes. \ud Conclusion These preliminary findings suggest that variations in mother-infant interaction dimensions are associated with differences in infant brain development. Although the study is cross-sectional and causation cannot be inferred, the findings reveal a dynamic interaction between brain and environment that may be important when considering interventions to optimize infant outcomes.
Databáze: OpenAIRE
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