The influence of sex and diet on the characteristics of hibernation in Syrian hamsters

Autor: Ate S. Boerema, J.J. Bruintjes, Robert H. Henning, Hjalmar R. Bouma, Cynthia M C Thissen, Marie Trefna, Maaike Goris, Edwin L de Vrij, Vera A Reitsema
Přispěvatelé: Van der Zee lab, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Eisel lab, Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Groningen Institute for Organ Transplantation (GIOT)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0106 biological sciences
0301 basic medicine
Hibernation
Male
Linoleic acid
Physiology
TAMIAS-STRIATUS
01 natural sciences
Biochemistry
FATTY-ACID-COMPOSITION
Polyunsaturated fat
chemistry.chemical_compound
Endocrinology
TORPOR PATTERNS
MESOCRICETUS-AURATUS
TEMPERATURE
chemistry.chemical_classification
GOLDEN-HAMSTERS
Fatty Acids
Unsaturated
Female
Polyunsaturated fatty acid
medicine.medical_specialty
Torpor
Hamster
Biology
010603 evolutionary biology
03 medical and health sciences
Mesocricetus auratus
FOOD
Internal medicine
Animals
Laboratory
MAMMALIAN HIBERNATORS
Sex differences
medicine
Animals
Syrian hamsters
Ecology
Evolution
Behavior and Systematics
Original Paper
Mesocricetus
Body Weight
biology.organism_classification
BODY-MASS
Diet
030104 developmental biology
chemistry
RICHARDSON GROUND-SQUIRRELS
Animal Science and Zoology
Zdroj: Journal of Comparative Physiology B, Biochemical, Systemic and Environmental Physiology, 187(5-6), 725-734. SPRINGER HEIDELBERG
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
ISSN: 1432-136X
Popis: Research on deep hibernators almost exclusively uses species captured from the wild or from local breeding. An exception is Syrian hamster (Mesocricetus auratus), the only standard laboratory animal showing deep hibernation. In deep hibernators, several factors influence hibernation quality, including body mass, sex and diet. We examined hibernation quality in commercially obtained Syrian hamsters in relation to body mass, sex and a diet enriched in polyunsaturated fatty acids. Animals (M/F:30/30, 12 weeks of age) were obtained from Harlan (IN, USA) and individually housed at 21 °C and L:D 14:10 until 20 weeks of age, followed by L:D 8:16 until 27 weeks. Then conditions were changed to 5 °C and L:D 0:24 for 9 weeks to induce hibernation. Movement was continuously monitored with passive infrared detectors. Hamsters were randomized to control diet or a diet 3× enriched in linoleic acid from 16 weeks of age. Hamsters showed a high rate of premature death (n = 24, 40%), both in animals that did and did not initiate torpor, which was unrelated to body weight, sex and diet. Time to death (31.7 ± 3.1 days, n = 12) or time to first torpor bout (36.6 ± 1.6 days, n = 12) was similar in prematurely deceased hamsters. Timing of induction of hibernation and duration of torpor and arousal was unaffected by body weight, sex or diet. Thus, commercially obtained Syrian hamsters subjected to winter conditions showed poor survival, irrespective of body weight, sex and diet. These factors also did not affect hibernation parameters. Possibly, long-term commercial breeding from a confined genetic background has selected against the hibernation trait. Electronic supplementary material The online version of this article (doi:10.1007/s00360-017-1072-y) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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