Flavone glucosides from
| Autor: | Okhundedaev, Bakhodir S., Bacher, Markus, Mukhamatkhanova, Rimma F., Shamyanov, Ildar J., Zengin, Gokhan, Böhmdorfer, Stefan, Mamadalieva, Nilufar Z., Rosenau, Thomas |
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| Rok vydání: | 2018 |
| Předmět: |
Antioxidant
DPPH medicine.medical_treatment Eupatilin Tyrosinase Flavonoid Plant Science 01 natural sciences Biochemistry Flavones Analytical Chemistry chemistry.chemical_compound Glucoside Glucosides medicine chemistry.chemical_classification Traditional medicine biology 010405 organic chemistry Chemistry Spectrum Analysis Organic Chemistry 0104 chemical sciences 010404 medicinal & biomolecular chemistry Artemisia Enzyme inhibitor biology.protein medicine.drug |
| Zdroj: | Natural product research. 33(15) |
| ISSN: | 1478-6427 |
| Popis: | A new flavone glucoside, 4',5-dihydroxy-3',5',6-trimethoxyflavone-7-O-β-D-glucoside was obtained from aerial parts of Artemisia juncea, together with the known flavone eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone). The compounds were comprehensively analytically characterized by IR, UV, NMR and HR-MS, and their chemical structures ascertained. The EtOAc fraction of A. juncea showed the strongest DPPH radical scavenging ability as well as reducing power (in CUPRAC and FRAP assays) and phosphomolybdenum activity. This fraction also exhibited the strongest inhibitory effects on tyrosinase. Additionally, the best antidiabetic effects were observed for eupatilin and the CHCl3 fraction. |
| Databáze: | OpenAIRE |
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