In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans
| Autor: | Ohene Adjei, M. R. W. Evans, Harry Thangaraj, M. H. Wansbrough-Jones, B. W. Allen, Françoise Portaels, D. K. Banerjee |
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| Rok vydání: | 2000 |
| Předmět: |
Microbiology (medical)
Mycobacterium Infections Nontuberculous Leprostatic Agents Microbial Sensitivity Tests Biology Microbiology Mycobacterium tuberculosis Anti-Infective Agents medicine Humans Uganda heterocyclic compounds Pharmacology (medical) Amikacin Antibacterial agent Pharmacology Mycobacterium ulcerans biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Anti-Bacterial Agents Ciprofloxacin Infectious Diseases Sparfloxacin Ofloxacin Rifampin Rifampicin Fluoroquinolones medicine.drug |
| Zdroj: | Journal of Antimicrobial Chemotherapy. 45:231-233 |
| ISSN: | 1460-2091 0305-7453 |
| DOI: | 10.1093/jac/45.2.231 |
| Popis: | MICs of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin were determined for 14 primary clinical isolates and three reference isolates of Mycobacterium ulcerans by modifying a standard agar dilution method for testing Mycobacterium tuberculosis sensitivity. All these antimicrobials were active against every isolate of M. ulcerans. Sparfloxacin exhibited the highest activity and ofloxacin was the least effective. Rifampicin exhibited the broadest range of activity. |
| Databáze: | OpenAIRE |
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