Irritable bowel syndrome-like symptoms in treated microscopic colitis patients compared with controls : a cross-sectional study
| Autor: | Ole B. Suhr, David Lundgren, Jenny Pagoldh, Pontus Karling |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Abdominal pain
medicine.medical_specialty Mixed anxiety-depressive disorder Gastroenterology and Hepatology calprotectin Gastroenterology Bloating Microscopic colitis Internal medicine medicine Gastroenterologi Irritable bowel syndrome AcademicSubjects/MED00260 irritable bowel syndrome business.industry microscopic colitis Original Articles medicine.disease anxiety Faecal calprotectin depression Anxiety medicine.symptom Calprotectin business |
| Zdroj: | Gastroenterology Report |
| Popis: | Background The prevalence of irritable bowel syndrome (IBS)-like symptoms is high in untreated patients with microscopic colitis (MC), but there is uncertainty of the prevalence of IBS-like symptoms in treated patients. We assessed the degree of IBS-like symptoms in patients with MC in comparison to control subjects, and investigated the association between IBS-like symptoms and faecal calprotectin (FC) in MC patients. Methods Patients with an established MC diagnosis (n = 57) were compared to sex- and age-matched controls (n = 138) for scores in the GSRS-IBS (Gastrointestinal Symptom Rating Scale for Irritable Bowel Syndrome) and HADS (Hospital Anxiety Depression Scale). In MC patients, an FC level was simultaneously analysed. Results The median interval from MC diagnoses to the time the subjects participated in the study was 5.5 years (25th–75th percentiles; 4.5–9.5 years). The total GSRS-IBS score, subscores for abdominal pain, bloating, and diarrhoea were significantly higher in MC patients compared to controls (all P Conclusions Patients with MC reported more IBS-like symptoms and anxiety than control subjects but neither FC levels nor symptoms of affectivity were significantly correlated with IBS-like symptoms. |
| Databáze: | OpenAIRE |
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