Ileitis due to Yersinia pseudotuberculosis in Crohn's disease
| Autor: | R Homewood, P.D Duane, A.P Griffiths, A Lewis, C.P Gibbons, D Richards |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
Adult Crohn's disease Exacerbation biology business.industry Terminal Ileitis Yersinia pseudotuberculosis Infections Disease Yersinia Ileitis biology.organism_classification medicine.disease digestive system diseases Serology Diagnosis Differential Infectious Diseases Crohn Disease Immunology medicine Yersinia pseudotuberculosis Humans Female business |
| Zdroj: | The Journal of infection. 47(4) |
| ISSN: | 0163-4453 |
| Popis: | We present the case of a young woman with fulminating terminal ileitis due to Yersinia pseudotuberculosis, in whom Crohn's disease was subsequently diagnosed. Serological testing was prompted by radiological, macroscopic and histological changes which were atypical of Crohn's disease. We speculate that Y. pseudotuberculosis ileitis may occasionally produce an acute exacerbation of Crohn's disease, but that its occurrence may not be diagnosed if the atypical features are not recognised. In this case, the classical features of Y. pseudotuberculosis may have been modified by pre-existing Crohn's disease. We propose that, because of defects in mucosal barrier function and immunological function, patients with Crohn's may have increased susceptibility to infection by Yersinia sp. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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