Comparison of RENAL, PADUA, CSA, and PAVP Nephrometry Scores in Predicting Functional Outcomes After Partial Nephrectomy
| Autor: | Brian R. Lane, John Anema, Stephen K. Babitz, Sabrina L. Noyes, Conrad M. Tobert, Ruchir Gupta, Marco Tori |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Urology medicine.medical_treatment 030232 urology & nephrology Renal function Collection system Kidney Nephrectomy 03 medical and health sciences 0302 clinical medicine Interquartile range Predictive Value of Tests Medicine Humans Aged Retrospective Studies business.industry Kidney pathology Reproducibility of Results Retrospective cohort study Organ Size Recovery of Function Middle Aged Kidney Neoplasms Treatment Outcome 030220 oncology & carcinogenesis Predictive value of tests Female business Nadir (topography) Glomerular Filtration Rate |
| Zdroj: | Urology. 124 |
| ISSN: | 1527-9995 |
| Popis: | Objective To evaluate the accuracy of radius, exophytic/endophytic, nearness to collecting system/sinus, anterior/posterior, and location relative to polar lines (RENAL), preoperative aspects and dimensions used for anatomical classification (PADUA), contact surface area (CSA), and preoperative assessment of volume preservation (PAVP) nephrometry scores in predicting postoperative renal functional outcomes after partial nephrectomy (PN). Few studies have compared the accuracy of tumor complexity systems directly in the same set of PN patients. Materials and Methods Patients treated with robotic, laparoscopic, or open PN having available imaging (n = 344) were examined. The ability of 4 systems to predict nadir estimated glomerular filtration rate (eGFR [median postoperative day 1]) and new baseline eGFR (median: 0.95 year) was analyzed using univariable and multivariable models. Results Median preoperative, nadir, and new baseline eGFR were 79 (interquartile range [IQR]: 63-97), 65 (IQR: 47-85), and 80 (IQR: 63-99) mL/min/1.73 m2. Multivariable models incorporating RENAL, PADUA, CSA, or PAVP were similarly predictive of postoperative renal function (nadir eGFR: R2 = 0.683-0.688, new baseline eGFR: R2 = 0.775). In univariable analysis, all 4 complexity systems were predictors of nadir GFR (each P Conclusion RENAL, PADUA, CSA, and PAVP are all predictors of early postoperative renal function. RENAL and PAVP provided the greatest predictive ability for later renal functional outcomes. |
| Databáze: | OpenAIRE |
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