Ethnic variations in the childhood prevalence of Hirschsprung disease in New Zealand
| Autor: | Askar Kukkady, Sasikumar Sankaran, Spencer W. Beasley, Lucy Goddard, Kiarash Taghavi, Mark D. Stringer, Stephen Evans, Jonathan Stevenson, Andrew Hobson |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Native Hawaiian or Other Pacific Islander Adolescent Population Ethnic group Disease Newly diagnosed Gene mutation White People 03 medical and health sciences 0302 clinical medicine Asian People Epidemiology Ethnicity Prevalence Operative report medicine Humans Hirschsprung Disease Child education Retrospective Studies Retrospective review education.field_of_study business.industry General Medicine Hospitalization Phenotype Child Preschool 030220 oncology & carcinogenesis Mutation Female 030211 gastroenterology & hepatology Surgery business New Zealand Demography |
| Zdroj: | ANZ Journal of Surgery. 89:1246-1249 |
| ISSN: | 1445-2197 1445-1433 |
| DOI: | 10.1111/ans.14857 |
| Popis: | BACKGROUND Epidemiological studies have suggested that there may be ethnic variations in the prevalence of Hirschsprung disease (HD) but no study has systematically investigated this issue or potential ethnic variations in the extent of aganglionosis in HD. This study aimed to investigate this in a childhood population in New Zealand. METHODS A multicentre national retrospective review was undertaken of all newly diagnosed cases of HD at each of the four paediatric surgical centres in New Zealand over a 16-year period (January 2000 to December 2015). Original histological, radiological and operative reports were obtained and analysed. Self-identified ethnicity was recorded from admission documents. Birth statistics were obtained from Statistics New Zealand. RESULTS A total of 246 cases of HD were identified. The prevalence of HD was 1:3790 live births for European, 1:6610 among Māori, 1:1834 among Pacific Peoples, 1:3847 among Asian and 1:5694 among Middle Eastern. The prevalence of HD was statistically significantly greater in Pacific Peoples (P |
| Databáze: | OpenAIRE |
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